Constantly on the run, membrane-bounded organelles (MBOs) in neurons deliver proteins from cell bodies to axons. A recent study by Scott Brady and colleagues at the University of Illinois suggests ...

Neurons depend heavily on efficient intracellular transport, perhaps more than any other type of cell. Two papers in Neuron provide evidence that proteins with expanded glutamine repeats, such as ...

Wild-type copper–zinc superoxide dismutase (SOD1) may cause sporadic amyotrophic lateral sclerosis (ALS) via a conformation and mechanism shared with mutant SOD1—a pathogenic factor in familial ...