Shortening timelines to generate more productive, stable, and high-expressing cell lines is the goal of any cell line development program. Here, we explore the advantages of combining of a technology ...

In the past few years, multispecific antibodies, such as trispecific, bispecific, and tetraspecific, have become popular in antibody therapeutics. Compared to conventional monospecific antibodies, ...

In a recent study posted to bioRxiv*, researchers evaluated how angiotensin-converting enzyme 2 (ACE2) expression in target cells impacts neutralization. Study: Receptor binding domain (RBD) ...

Monoclonal antibodies have become one of the most established and clinically successful therapeutic modalities, supported by ...

Antibody engineering and production are essential tools in drug discovery, providing powerful and specific therapeutics and diagnostic/prognostic materials for various diseases. Antibodies are ...

Non-CHO cell expression systems gain traction as faster, more flexible alternatives for biologics manufacturing.

Antibody engineering enables the generation of novel and diverse antibody constructs. The development of therapeutic antibodies is highly dependent on antibody engineering, whether for the generation ...

Antibody-drug conjugates (ADCs) have reshaped the cancer treatment landscape across a variety of different tumor types. ADCs' peculiar pharmacologic design combines the cytotoxic properties of ...

The history of antibody engineering and production in drug discovery can be traced back to the 1970s and 1980s [1] when scientists first began to explore the potential of using antibodies as ...