This is a preview. Log in through your library . Abstract We have used pulse-chase metabolic radiolabeling with L-[35 S]methionine in conjunction with subcellular fractionation and specific protein ...

This is a preview. Log in through your library . Abstract A procedure employing streptolysin O to effect the selective permeabilization of either the apical or basolateral plasma membrane domains of ...

To overcome the challenges of the existing model systems, researchers developed organoids, which are 3D multicellular structures. Organoids contain multiple organ-specific cell types interacting with ...

Cells talk to each other to coordinate nutrition, waste removal, energy use, and, in some cases, disease progression. The cells that line the surfaces of organs or specific tissues, called epithelial ...

While new drug molecules are typically tested in vivo in two preclinical species to better understand how they are transported and eliminated by the kidney and assess the risk of renal toxicity in ...

Researchers in the United States have provided important insights into the pathophysiology of diarrhea that occurs in some cases of coronavirus disease 2019 (COVID-19). The team says the “COVID-19 ...