Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have ...

Blood cancers such as leukemia are caused by genetic changes in the blood-forming stem cells of the bone marrow. Scientists at the University Medical Center Mainz have now shown how chronic ...

The map was developed by using single-cell RNA sequencing to analyze 1.4 million plasma and immune cells in bone marrow from over 300 patients.

Inflammation covertly rewires the bone marrow, enabling mutated stem cells to rise and setting the stage for future blood disease.

Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to quietly gain dominance with age. Reprogrammed stromal cells and interferon ...

Treg therapeutic designed to preferentially traffic towards its ligand CXCL12 over expressed in the bone marrow and spleen in myelofibrosis. -- CK0804 engages with antigen presenting cells within ...

CK0804, a regulatory T cell therapy, received FDA orphan drug designation for myelofibrosis, supporting rare disease treatment development. Clinical study results showed significant reductions in ...

A bone marrow transplant, or stem cell transplant, places blood stem cells back into the body. The transplant replaces cells that cancer or treatments have destroyed. People may have a bone marrow ...

Agent orange vector illustration word cloud isolated on a white background. Agent Orange exposure is linked to a rare bone marrow cancer Vietnam veterans exposed to Agent Orange had a higher risk of ...