Cytomegalovirus (CMV) infection sometimes causes large expansions of CMV-specific T cells, particularly in older people. This is believed to undermine immunity to other pathogens and to accelerate ...
Study is the first randomized, controlled trial examining a vaccine’s effectiveness in controlling CMV in recipients of HSCT from vaccinated donors Encouraging pilot study results demonstrated the ...
Effect of phosphoinositide-phospholipase c beta1 monoallelic deletion in low-risk MDS patients treated with darbepoetin. Background: Human cytomegalovirus (CMV) infects between 50%-85% of adults and ...
ITI’s dendritic cell vaccine is designed to target the pp65 viral antigen of Cytomegalovirus (CMV) that is expressed in GBM, but not in normal brain cells. In the ATTAC studies, the GBM patients’ ...
From the Boeckh, Bradley, and Prlic Labs, a collaboration between the Vaccine and Infectious Disease, Clinical Research, and Public Health Sciences Divisions This project originated when a unique set ...
Organ and hematopoietic stem cell transplants (HSCTs) are life-saving treatments, but come with certain risks, like viral infection. Because some degree of immune suppression is required for the ...
A new study indicates that noninvasive prenatal screening (NIPS) performed using a low-cost form of whole genome sequencing can detect pregnant mothers at risk for transmitting cytomegalovirus (CMV) — ...
Recent $11.3 million grant from the California Institute for Regenerative Medicine (CIRM) intended to fund the Phase 1 clinical trial at City of Hope; the Investigational New Drug application for ...
A UCLA research team has found a new way to prompt the immune system to kill cells infected with cytomegalovirus (CMV), a life-threatening infection that is particularly deadly in immunocompromised ...