In a recent study posted to the medRxiv* preprint server, researchers determined the immune mechanisms associated with severe neurological manifestations of coronavirus disease 2019 (COVID-19). Study: ...

OTTAWA, Ontario — Looking for Alzheimer’s disease (AD) biomarkers in plasma instead of cerebrospinal fluid (CSF) is a simpler form of screening individuals for AD pathology and could result in earlier ...

Cerebrospinal fluid and plasma markers are now being used to help diagnose Alzheimer’s in memory clinics, but what about using them to stage the disease? That’s the next big step, said Henrik ...

CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.

A commercially available plasma phosphorylated-tau217 assay was highly accurate in identifying Alzheimer disease pathology. The plasma phosphorylated tau (p-tau) at threonine 217 (p-tau217) ...

Scientists believe that poor clearance of Aβ from the brain underlies sporadic Alzheimer’s disease. Now, evidence for subtle changes in the plasma levels of Aβ1-42 seems to back that up. At this ...