Perhaps no cell type uses calcium in as many ways as does a cardiac myocyte. In addition to its well-known involvement in regulating cardiac contractility, recent studies have emphasized the ...

Calcium/Calmodulin-dependent Protein Kinase Kinase 2 (CaMKK2) has emerged as a pivotal molecule in transducing calcium signals via its interaction with calmodulin. This kinase modulates several ...

Thomas J. Hund, Ph.D., post-doctoral researcher in Pathology ( in Dr. Jeffrey Saffitz laboratory) at the Washington University School of Medicine, and Yoram Rudy, The Fred Saigh Distinguished ...

Glycine, a non-essential amino acid derived from serine, plays an increasingly recognized role in metabolic regulation. Epidemiological studies consistently show that reduced circulating glycine ...

A recent review published in the journal Molecular Psychiatry explores the calcium-calmodulin-dependent protein kinase kinase-2 (CaMKK2) signaling pathway as a contributor to bipolar disorder ...

It is vital to the regulation of cell activities through its role as a second messenger. Calcium signaling is the process whereby low cytoplasmic concentrations are deliberately increased to activate ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

A technique for measuring the cardiac risk associated with cobalt-containing hip replacements has been highlighted for the first time in research at the University of Strathclyde. Science X Daily and ...