New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

A woman with hopes to conceive was diagnosed with severe vasospastic angina (VSA); however, she was able to carry a healthy baby to full term without angina attacks after starting treatment of a ...

What is the best approach for a patient with worsening renal insufficiency and intolerance of ACE inhibitors or angiotensin receptor blockers (ARBs)? —Ann Marchetta, MS, ARNP-C, FNP, Waupaca, Wis.

Voltage‐gated calcium channels, particularly the CaV2.1 channels encoded by the CACNA1A gene, are central to cerebellar function and synaptic transmission. Dysfunction in these channels leads to a ...

Please provide your email address to receive an email when new articles are posted on . An ongoing study showed improvements in SSc severity, disease-related pain, Raynaud’s symptoms and ...

Examining data on more than 400,000 participants in the U.K. Biobank revealed that use of CCBs was associated with a 39% greater odds of glaucoma after adjusting for various factors, including the use ...

A woman with hopes to conceive was diagnosed with severe vasospastic angina (VSA); however, she was able to carry a healthy baby to full term without angina attacks after starting treatment of a ...

Hand opening pill bottle Clearer guidelines for diuretic management in patients with chronic kidney disease are needed, according to investigators. Adding diuretics rather than calcium channel ...

An essential protein that acts as a gatekeeper for calcium entering cells promotes the growth of oral cancer and generates pain, according to a new study. Targeting this protein -- the ORAI1 calcium ...

Calcium channel blocker toxicity represents a significant clinical challenge owing to its multifaceted pathophysiology and potential to precipitate life‐threatening cardiovascular compromise. Overdose ...