(a) Within this simple eukaryotic transcriptional unit, a simple core promoter (TATA), an upstream activator sequence (UAS), and a silencer element are spaced within 100 to 200 base pairs of the TATA ...

In their upcoming G&D paper, Dr. Robert Tjian (UC Berkeley) and colleagues reveal how histone gene expression is differentially regulated during Drosophila development. The researchers demonstrate ...

Yeast is a single cell eukaryotic organism, that incites in this Irish scientist an intense memory of the smell of brewing Guinness, wafting down the River Liffey on a drizzly Dublin day as I sit at ...

Different mechanisms have been proposed to explain the specificity of enhancer-promoter interactions, including promoter competition and insulator DNA elements. In the 9 July Proceedings of the ...