Recent trends in directed enzyme evolution focus on combining high-throughput screening methods with advanced biophysical tools and data-driven computational approaches. However, these methods pose ...
Enzymes are molecular machines that carry out the chemical reactions that sustain all life, an ability that has captured the attention of scientists like me. Consider muscle movement. Your body ...
Frances Arnold, 2018 recipient of the Nobel Prize in Chemistry, was presented the Tufts' Department of Chemistry's Max Tishler Award in the Pearson Chemical Laboratory on Thursday. Arnold is the Linus ...
In nature, evolution takes years to sculpt new traits. In the lab, scientists hope to achieve this feat much faster: Being able to evolve proteins with enhanced or novel functions has important ...
Enzymes catalyze chemical reactions in organisms - without which life would not be possible. Leveraging AlphaFold2 artificial intelligence, researchers at Charité – Universitätsmedizin Berlin have now ...
Enzymes evolved to efficiently operate in low-temperature environments via key substitutions of amino acids in their active site, which lowers the activation energy of catalytic reactions. Life has ...
For the first time, scientists have engineered an enzyme that can break stubborn man-made bonds between silicon and carbon that exist in widely used chemicals known as siloxanes, or silicones. The ...
A new peer-reviewed study by researchers at The University of Texas at Austin (UT at Austin) shows how artificial intelligence (AI) machine learning can help guide and improve enzyme design for the ...