While the large proportion of our genome that does not instruct our cells to form proteins has been harder to study than protein-coding genes, it has been shown to have vital physiological functions.

Using STING-seq, short for systematic targeting and inhibition of noncoding GWAS loci with single cell sequencing, Sanjana and his team identified promising sequence variants linked to various ...

A novel bioinformatics approach for classifying proteins according to similarity of function, rather than of sequence, is described in the April 12 PNAS. Albert Y. Lau and Daniel I. Chasman of ...

The expression pattern of a single gene or multiple genes can be investigated using a technique RNA microarray. In this technique, RNA molecules are ‘spotted’ onto a solid surface. These act as probes ...

Have you ever found yourself endlessly dragging that little Excel fill handle, trying to populate rows or columns with numbers, dates, or formulas? It’s tedious, time-consuming, and let’s be ...

AI protein function prediction uses machine learning models trained on sequence and structural data to infer protein roles at ...

Amgen manufactured and sold PCSK9 inhibitor Repatha whereas Sanofi manufactured and sold PCSK9 inhibitor Praluent, for the treatment of hyperlipidemia. In 2019, Repatha enjoyed a 70% share of the ...

The SystemVerilog universal verification methodology (UVM) is an efficient way to generate tests and check results for functional verification, best used for block level IC or FPGA or other “smaller” ...