Gap junctions are specialised intercellular channels that facilitate direct communication between adjacent cells by allowing the regulated exchange of ions, second messengers and small metabolites.

The emergence of gap junctions is a hallmark in the evolution of life from single-cell to multicellular organisms. For the first time, they enabled true social interactions between cells by allowing ...

When two cells "talk" to each other, they often do so through tiny channels called electrical synapses. Unlike chemical synapses, these so-called gap junctions enable the direct exchange of ...