CKY Ng, HN Pemberton and JS Reis-Filho are funded by Breakthrough Breast Cancer. The authors also acknowledge NHS funding for the National Institute of Health Research Biomedical Research Centre. The ...

Most cancers are not driven by a single gene mutation, but rather an accumulation of mutations that develop over the evolution of tumor growth. While mouse models are useful for identifying cancer ...

Please provide your email address to receive an email when new articles are posted on . NASHVILLE, Tenn. — An analysis of germline susceptibility to renal cell carcinoma revealed considerable ...

Charcot-Marie-Tooth (CMT) disease is a group of clinically and genetically heterogeneous sensorimotor peripheral neuropathies ...

Forty-five years ago adult AL was incurable. Since then we have discovered the striking heterogeneity of AL and its importance in selecting therapy, resulting in cure of increasing numbers of patients ...

Researchers have developed a light-induced DNA detection method that enables rapid, PCR-free genetic analysis. Their technique offers ultra-sensitive mutation detection in just five minutes, reducing ...

The power of CRISPR became definitively clear when the first CRISPR-based gene therapy, Casgevy (exa-cel), won regulatory approvals for the treatment of sickle cell disease. But CRISPR’s applications ...

Machine learning models are designed to analyze large, heterogeneous datasets and identify complex relationships without ...

For the families affected by autism, the most haunting and important question is if autism is genetic? The response, though complicated, increasingly leans toward a strong genetic component, albeit ...