Hypertonic resuscitation – a concentrated intravenous (IV) dose of saline and dextran, a sugar solution – has the potential to help survivors of blunt trauma by improving blood flow and delivery of ...

Hypertonic saline and mannitol show similar effects on mortality and intracranial pressure control in children with TBI.

There are several theoretical benefits associated with the use of hypertonic saline with regard to hemodynamics, immune modulation, and ICP reduction. TBI is a disruption of the normal function of the ...

The glymphatic system enables the flow of cerebrospinal fluid to the brain tissue, particularly during sleep, enabling the fluid to cleanse the tissue and carry accumulated metabolites with it towards ...

THE application of hypertonic solutions speeds the appearance of clinical signs of cellular dehydration in proportion to the impermeability of the cellular membrane. Intravenous infusion of hypertonic ...

Distinguishing between arginine vasopressin (AVP) deficiency and primary polydipsia is challenging. Hypertonic saline–stimulated copeptin has been used to diagnose AVP deficiency with high accuracy ...

Please provide your email address to receive an email when new articles are posted on . The mean number of pulmonary exacerbations did not significantly differ among those receiving vs. not receiving ...

Researchers at the University of São Paulo (USP) in Brazil have shown that a hypertonic saline solution inhibits replication of SARS-CoV-2, the virus that causes COVID-19, and have elucidated the ...

Abnormal homeostasis of the volume of airway surface liquid in patients with cystic fibrosis is thought to produce defects in mucus clearance and airway defense. Through osmotic forces, hypertonic ...

Am J Health Syst Pharm. 2010;67(22):1920-1928. Due to the high osmolarity of hypertonic saline, infusion through a central line is preferred to minimize phlebitis. Most studies used a 7.5% hypertonic ...