The insulin receptor (IR) is a prototypical receptor tyrosine kinase that orchestrates critical cellular processes, including metabolism, cell growth and differentiation. Activation of the IR involves ...

An analysis of insulin-controlled proteins in the skeletal muscle of genetically distinct mice sheds light on the interplay between genes and diet in type 2 diabetes. Researchers have produced a ...

A new study focuses on the insulin receptor to understand its role in the development of type 2 diabetes mellitus, a metabolic disease with a major impact on global health. Insulin resistance precedes ...

Researchers have produced a comprehensive picture of insulin signaling in mice and suggest that it is shaped by entangled effects of genetics and diet. The research, published today as a Reviewed ...

Type 2 diabetes has long been framed as a story of calories, weight and willpower, but a growing body of research is shifting ...

A new study uncovers how endothelial cells contribute to insulin resistance in obesity-associated diabetes, highlighting adrenomedullin as a potential therapeutic target. Study: Endothelial insulin ...

Researchers have produced a comprehensive picture of insulin signalling in mice and suggest that it is shaped by entangled effects of genetics and diet. Researchers have produced a comprehensive ...