Long-Term Incidence and Predictors of Significant Hearing Loss Requiring Hearing Assistive Devices Among Childhood Cancer Survivors: A Population-Based Study Postinduction CNS prophylaxis with ITT did ...

Aug. 2, 2002 -- Prophylactic intrathecal methotrexate significantly reduced recurrence and improved survival for patients in complete remission from aggressive non-Hodgkin's lymphoma (NHL), according ...

We defined a case as onset from January 1 to October 31, 2007, of bilateral flaccid paraparesis or paraplegia or retention and incontinence of stool or urine, in a patient receiving intrathecal drugs.

We describe the clinical spectrum of IT MTX-related SLS, reported in detail in 31 patients treated as part of the UKALL 2003 trial. Concomitant administration of IV cyclophosphamide and cytosine ...

Between 1993 and 1999, 1395 children with ALL (778 boys, 617 girls) were enrolled in the FRALLE 93 study. Informed consent was obtained from all patients’ parents in accordance with national ethic ...

Methotrexate 300 mg/m 2 by iv. infusion over 12 h Day 2 Etoposide 100 mg/m 2 by iv. infusion over 30 min Actinomycin D 0.5 mg iv. bolus Folinic acid rescue 15 mg orally every 12 h for four doses ...

Accord Healthcare, a London-based drugmaker, resumed manufacturing of two methotrexate solutions, according to a Nov. 7 update from the FDA. By March, the American Society of Health-System Pharmacists ...