Please provide your email address to receive an email when new articles are posted on . Sometimes we forget what we learned in pre-Med. There is variability in most tests we order from the clinical ...

Recently, FDA told a medical device start-up company that, in regard to the company’s proposed clinical trial, “The equivalence of the device to the predicate can be demonstrated if the confidence ...

A confidence interval is a statistical concept that shows how likely it is that a range based on a sample of a population contains the mean, or the actual figure, for that data set. It’s useful when a ...

A modified sequential procedure is put forward for the problem of estimating the mean of a normal population by a confidence interval of prescribed width and confidence coefficient, when the ...

In controlled group sequential trials, we consider the ratio of normal means as the effect measure of interest and derive group sequential nested confidence intervals on this parameter. In an interim ...