Bacillus subtilis has emerged as a pre‐eminent model organism for the study and application of protein expression and secretion, owing to its robust secretory pathways and genetic tractability. Its ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
Enodia Therapeutics, a biotechnology company developing novel small-molecule therapies for targeted protein degradation at ...
Bacterial interaction with plants and animals, symbiotic or pathogenic, involves the transfer to host cells and tissues of a range of bacterial proteins whose biochemical activities are key to ...
A group of international researchers reports the availability of a new “map”’ of every gene, protein, and metabolic pathway required for a cell to efficiently secrete recombinant proteins. The team, ...
Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...
A recent study published in the journal Frontiers in Endocrinology investigated the role of the short-chain dehydrogenase/reductase 42E member 1 (SDR42E1) enzyme in regulating sterol metabolism and ...
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