Nature

Inhibition of Proteolytic Enzymes by Decarboxylated Amino-Acid Derivatives. Effect of Toluenesulphonyl(Tosyl)agmatine (4-Toluenesulphonamidobutylguanidine) on Thrombin and Trypsin

PROTEOLYTIC enzymes are known to catalyse the hydrolysis of specific amino-acid esters and amides 1. Specificity is usually determined by the side-chain of the amino-acid contributing the carbonyl ...
The New England Journal of Medicine

Serum Proteolytic Enzyme Activity in Pancreatic Disease

This report concerns our observations of serum proteolytic activity in . . . From the Gastrointestinal Research Laboratory and the Department of Medicine, Seton Hall College of Medicine, and the ...
ascopubs.org

The effect of proteolytic enzyme-containing gargling agents on severe stomatitis caused by therapy for head and neck cancer.

Expression of interleukin-1α (IL1-α) and risk of distant metastases (DM) in head and neck squamous cell carcinoma (HNSCC). This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This ...
News Medical

Proteolytic cleavage of nucleocapsid helps SARS-CoV-2 evade host immune responses

A team of scientists of the University of Oxford reveals that the nucleocapsid protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) undergoes autoproteolysis, and that resulting ...