Sickle cell disease—the subject of a new Seminar in The Lancet—is one of the most prevalent and fastest-growing genetic disorders worldwide. Although its true prevalence is difficult to determine ...

Doctors say new gene-based treatments could offer long-term relief — and possible cures — for people living with sickle cell disease. Sickle cell disease has long shortened lives in the United States, ...

Sickle cell disease is inherited at birth when you receive related genes from both parents. One gene usually causes sickle cell trait (SCT), which often has no health problems. The main sickle cell ...