In response to chronic stimuli such as alcohol abuse, viral infection, NAFLD/NASH and toxic damage, liver loses its normal structure and non-parenchymal cells including HSCs, KCs and LSECs undergo ...

Daix (France), New York City (New York, United States), July 2, 2025 – Inventiva (Euronext Paris and Nasdaq: IVA) (“Inventiva” or the “Company”), a clinical-stage biopharmaceutical company focused on ...

Scientists have discovered a new type of cell in the liver that plays a critical role in repairing damage. These "leader cells" are responsible for dragging healthy tissue into wounds as they heal ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

Integrated map of scRNA-seq and snRNA-seq data from pig livers at four time points and cellular heterogeneities within each major hepatic cell types. This study is led by Prof. Lusheng Huang (National ...

A team of researchers has uncovered a previously unknown compensatory mechanism found in liver disease. If Kupffer cells (KCs), a specific kind of immune cells found in the liver, become impaired by ...

Scientists from the Karolinska Institute in Sweden report that immune cells in the liver react to high cholesterol levels and engulf excess cholesterol that can otherwise cause damage to arteries.

Excessive alcohol consumption causes alcoholic liver disease, and about 20% of these cases progress to alcohol-associated steatohepatitis (ASH), which can lead to liver cirrhosis and liver failure.