To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Serine serves as a metabolic nexus in tumors, coordinating one-carbon metabolism, nucleotide synthesis, and redox regulation. In recent years, targeting the serine metabolic pathway, particularly the ...

Recent advances in optical physics have redefined the classical boundaries imposed by diffraction. Super-resolution imaging techniques, which once adhered strictly to the Rayleigh criterion, now ...

A recent study published in the journal Cell Reports Physical Science introduced a novel super-resolution imaging technique called resonant multi-focal scanning microscopy (RSM). The objective was to ...

There is a growing demand for non-invasive insights into the complex three-dimensional subcellular dynamics within living tissues on the frontier of biological research. To achieve simultaneous ...

Researchers devised a way to expand tissue 20-fold in a single step. Their simple, inexpensive method could pave the way for nearly any biology lab to perform nanoscale imaging. A classical way to ...

Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

Existing super-resolution techniques still face considerable challenges in complex deep tissue environments. For example, Stimulated Emission Depletion (STED) microscopy relies on a doughnut-shaped ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Researchers have demonstrated that consumer-grade 3D printers and inexpensive materials can produce advanced optical ...

Scientists have unveiled a new way to capture ultra-sharp optical images without lenses or painstaking alignment. The ...