For the first time, researchers have found one of the most important molecular machines in our cells uses a ‘twisting elevator’ mechanism, solving a mystery of how it transports crucial chemical ...

In this slice through the structure of human serotonin transporter, (S)-citalopram binds to both the central (green) and allosteric (blue) binding sites. Drug designers have long been synthesizing ...

For the first time, scientists have solved the high-resolution structure of the molecular transporter TSPO, which introduces cholesterol into mitochondria. This protein also serves as a docking site ...

(Memphis, Tenn.—May 23, 2023) Scientists at St. Jude Children’s Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved ...

This study systematically elucidates the multifunctional transport properties and structural basis of BTR1, a member of the SLC4 ...

Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity. They ...

Pi plays crucial metabolic and structural roles in living organisms. It is essential for bioenergetics (ATP, GTP), metabolic regulation through glycolysis and oxidative phosphorylation, intercellular ...

Using nuclear magnetic resonance (NMR) spectroscopy, chemists have discovered how the structure of E. coli’s EmrE efflux pump—a transporter that can pump toxic molecules like antibiotics out of ...

Plants are surrounded by and closely associated with microbes. The majority of these are beneficial, but some can cause devastating disease. Plants feed these microbes just enough to allow the good ...

This news release is available in German. The word "cholesterol" is directly linked in most people's minds with high-fat foods, worrying blood test results, and cardiovascular diseases. However, ...