Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. An international team of ...

One in every three FDA-approved drugs targets a single superfamily of receptors dotting the surfaces of human cells. From beta blockers to antihistamines, these essential, life-saving medications ...

Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

A drug interaction happens when a substance affects how a drug behaves in the body. Some substances that can cause interactions include other drugs, supplements, food, and alcohol. Drug interactions ...

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...

GLP-1 receptor agonists, a class of drug used to treat type 2 diabetes, likely trump the widely prescribed metformin for curbing dementia risk in people with the condition, finds the largest study of ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...