The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

When the body experiences an injury to a blood vessel, muscular response to the injury causes the vessel to constrict, decreasing blood flow to the area. The blood is exposed to collagen in the ...

Under homeostatic conditions, the body is maintained in a finely tuned balance of coagulation and fibrinolysis. See Figure 1 for a depiction of normal hemostasis. The activation of the coagulation ...

A recent study provides new insights into the mechanisms of coagulation in persons with haemophilia A, the most common form of haemophilia. The research team was able to show that saliva contains ...

Coagulation is the process of making blood clot. This is an important and complex process that enables the blood to plug and heal a wound. This is how the body stops any unwanted bleeding. Coagulation ...