A new strategy to beat lung cancer: Chemists develop first-in-class inhibitor targeting a key epigenetic regulator

A research team has made a breakthrough in epigenetic drug discovery. The researchers have successfully developed a ...
Technology Networks

Epigenetic Drug Switches Off Tumor-Driving Genes in Lung Cancer

Researchers developed LS-170, an inhibitor of the ATAC complex, which suppressed oncogene expression and reduced tumor growth ...

Golden Gate method enables fully-synthetic engineering of therapeutically relevant bacteriophages

Bacteriophages have been used therapeutically to treat infectious bacterial diseases for over a century. As ...
eLife

A retrospective analysis of 400 publications reveals patterns of irreproducibility across an entire life sciences research field

The ReproSci project retrospectively analyzed the reproducibility of 1006 claims from 400 papers published between 1959 and 2011 in the field of Drosophila immunity. This project attempts to provide a ...

Breakthrough in Epigenetic Drug Discovery Targets Tumor Growth in Lung Cancer

In a groundbreaking advancement for cancer treatment, a research team led by Professor Xiang David Li from the Department of Chemistry at The University of Hong Kong (HKU) has made significant strides ...
The Scientist

Optimizing Oxford Nanopore Long-Read Whole Genome Sequencing of Salivary DNA Using Oragene™ Collection Devices

Saliva is an easily accessible source of high molecular weight DNA for Oxford Nanopore long-read sequencing applications.