A fact sheet about the BRCA1 and BRCA2 genes, what to do if a person tests positive for alterations in one of these genes, and consequences of genetic testing.

Germline pathogenic variants in BRCA1/BRCA2 are associated with ovarian cancer, fallopian tube cancer, primary peritoneal cancer, male breast cancer, prostate cancer, pancreatic …

A gene that makes a protein that repairs damaged DNA. Mutations (changes) in the BRCA1 gene significantly increase the risk of developing breast and ovarian cancer.

Hoja informativa sobre los genes BRCA1 y BRCA2, qué hacer si la prueba de una persona indica que tiene cambios en uno de estos genes y las consecuencias de las pruebas genéticas.

Gen que da origen a una proteína que repara el ADN dañado. Las mutaciones (cambios) en el gen BRCA1 aumentan mucho el riesgo de presentar cáncer de mama y cáncer de ovario.

These gene mutations are associated with an often aggressive form of breast cancer as well as ovarian cancer. Identification of the BRCA1 gene mutation by NCI-supported scientists as a …

Apr 15, 2024 · For women in whom gene testing finds “harmful changes” in the BRCA1 or BRCA2 genes, leading medical groups recommend that they take specific actions to lower their …

Apr 24, 2025 · The concern is especially acute for women with inherited mutations in the BRCA1 and BRCA2 genes, who have a 30- to 40-fold increased risk of ovarian cancer compared with …

BRCA1 is a nuclear phosphoprotein that functions as a tumor suppressor. BRCA1 combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi …

Aug 22, 2017 · Los códigos de los genes BRCA1 y BRCA2 de proteínas esenciales para que las células reparen el ADN dañado. Mutaciones específicas heredadas en estos genes aumentan …