
CooA - Wikipedia
CooA is a heme -containing transcription factor that responds to the presence of carbon monoxide. This protein forms homodimers and is a homolog of cAMP receptor protein.
CO-Mediated Allostery in CooA – Burstyn Lab – UW–Madison
The most-studied homolog of CooA from the purple photosynthetic bacterium, Rhodospirillum rubrum, senses both the presence of CO and the redox potential in the cell to regulate …
Dynamics of Carbon Monoxide Binding to CooA
CooA is a dimeric CO-sensing heme protein from Rhodospirillum rubrum. The heme iron in reduced CooA is six-coordinate; the axial ligands are His-77 and Pro-2. CO displaces Pro-2 …
Structure of the CO sensing transcription activator CooA
CooA is a homodimeric transcription factor that belongs to the catabolite activator protein (CAP) family. Binding of CO to the heme groups of CooA leads to the transcription of genes involved...
Regulatory transcription factor (CooA)-driven carbon monoxide …
Jun 1, 2023 · The proposed biosensor is based on utilizing CooA, a dimeric CO-sensing transcription factor and activator of R. rubrum, as the core component. CooA is a CODH …
Mechanistic Studies of the Carbon Monoxide Sensor CooA
CooA is a protein found in Rhodospirillum rubrum (Rr) and Carboxydothermus hydrogenoformans (Ch) and is both a carbon monoxide (CO) sensor and transcription factor. When CO binds to a …
CooA – Knowledge and References – Taylor & Francis
CooA is a protein found in Rhodospirullum rubrum that contains a hemebinding domain and a DNA-binding domain, which work together to regulate the induction of genes involved in CO …
Probing conformational dynamics of DNA binding by CO-sensing ...
The transcription factor CooA is a CRP/FNR (cAMP receptor protein/ fumarate and nitrate reductase) superfamily protein that uses heme to sense carbon monoxide (CO).
Spectroscopic Interrogation of Thiolate Hydrogen Bonding in the …
May 21, 2025 · The CO-sensing transcription factor from Rhodospirillum rubum, Rr CooA, is the best-characterized type-2 heme thiolate protein and is well-suited to study thiolate hydrogen …
Activation Mechanism of the CO Sensor CooA - Journal of …
Sep 12, 2003 · CooA is a CO-dependent heme protein transcription factor of the bacterium Rhodospirillum rubrum. CO binding to its heme causes CooA to bind DNA and activate …