Degranulation in mast cells is part of an inflammatory response, and substances such as histamine are released. Granules from mast cells mediate processes such as "vasodilation, vascular homeostasis, …

Jul 20, 2025 · Degranulation is a cellular process where immune cells release biologically active molecules from internal compartments called granules. This action is a component of the body’s …

Degranulation is defined as the process by which neutrophils release the contents of their vesicles, either into the extracellular space or into phagocytic vacuoles to form phagolysosomes, facilitating …

Degranulation is the process by which immune cells, particularly mast cells and basophils, release their pre-stored granules containing various biologically active substances, including histamines and …

The meaning of DEGRANULATION is the process of losing granules; specifically : the process by which cytoplasmic granules (as of mast cells) release their contents.

…the neutrophil are depleted (degranulation). A metabolic process within the granules produces hydrogen peroxide and a highly active form of oxygen (superoxide), which destroy the ingested …

Cell reaction that releases antimicrobial cytotoxic molecules and other substances (e.g., histamine) from secretory vesicles called granules found inside some cells.

Antigens interact with IgE molecules already bound to high affinity Fc receptors on the surface of mast cells to induce degranulation. The mast cell releases a mixture of compounds, including histamine, …

Degranulation of mast cells involves a two-step process, report Nishida et al. on page 115. First, antigen stimulation triggers microtubule polymerization and granule translocation to the cell surface in a …

In degranulation, substances such as histamine are released into the circulation. Although degranulation as an immune response can cause an allergic reaction, it can also kill pathogens.