Jul 24, 2025 · A neomorphic mutation is unique because it creates a qualitatively new effect, not just more of the existing effect or an antagonistic effect. The dose of the normal gene product …

A neomorphic mutation can cause ectopic mRNA or protein expression, or new protein functions from altered protein structure. Changing wildtype gene dose has no effect on the phenotype of …

These neomorphic mutations, which can be found in both tumor suppressor genes and oncogenes, produce proteins with entirely different functions from their respective wild-type …

Jul 28, 2021 · Neomorphic mutation or neomorph leads to a new gene activity. It differs from hypermorphic and antimorphic mutations in a way that the dose of wild-type has no effect on …

Jan 6, 2026 · The meaning of NEOMORPH is a structure that is not derived from a similar structure in an ancestor.

There are four meanings listed in OED's entry for the adjective neomorphic, one of which is labelled obsolete. See ‘Meaning & use’ for definitions, usage, and quotation evidence.

A type of mutation in which the altered gene product possesses a novel molecular function or a novel pattern of gene expression. Neomorphic mutations are usually dominant or …

The classical neomorphic mutation is a translocation that moves a new regulatory element next to a gene promoter so it is expressed in a new tissue or at a new time during development.

A Neomorphic mutation causes a dominant gain of gene function that is different from the normal function. A neomorphic mutation can cause ectopic mRNA or protein expression, or new …

Nov 14, 2016 · These neomorphic mutations, which can be found in both tumor suppressor genes and oncogenes, produce proteins with entirely different functions from their respective wild …